Mehrotra d, prandhan r, gupta s 2009 retrospective comparison of surgical treatment modalities in 100 patients with oral submucous fibrosis. A 20yearold patient with oral submucous fibrosis was treated with contact diode laser under local anesthesia and was followed up for six months. The condition was prevalent in the days of sushruta 600 bc, a great practitioner of ancient medicine labeled this condition as vidhari. The management of osmf depends largely upon the mucosal changes. Oral sub mucous fibrosis is a crippling disease of mouth with high malignant potential that has high prevalence rate in india and south east asia. Various medical and surgical treatment modalities have been used in modern science, but results are not satisfactory owing to recurrence, adverse effects, and sometimes worsening the condition.
Application of the buccal fat pad to the surgical treatment of oral submucous fibrosis. Information for patients charles clifford dental hospital. More general information, not necessarily in relation to oral submucous fibrosis, on hospital and medical facility performance. Oral submucous fibrosis treatment peoplebeatingcancer. Oral submucous fibrosis is a well known clinical entity since the time of sushruta as vidari. Oral submucous fibrosis is a disease due to a chronic, insidious change in fibroelasticity, characterized by burning sensation in the oral cavity, blanching, and stiffening of the oral mucosa and oropharynx leading to trismus and inability to open the mouth. Efficacy of hyaluronidase combined with corticosteroids in treatment. Contents introduction definition epidemiology nomenclature classification etiopathogenesis clinical features histopathology differential diagnosis special investigations malignant potential treatment and management.
Although occasionally preceded andor associated with vesicle formation, is. Spirulina was used for the first time for treatment of oral submucous fibrosis osmf and it proved to be superior than pentoxyfilline as no side effects were observed. Comparison of mouth opening with different nonsurgical. Oral submucous fibrosis surgical treatment surgery may be required if the fibrosis continues to progress despite all the above treatments and the interincisal distance gets below 2 cm. Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis. Oral submucous fibrosis osmf is a disease of unknown etiology. Oral surg oral med oral pathol oral radiol endod 1073. It causes inflammation and progressive thickening of the lining of the mouth. It is a chronic and highrisk precancerous condition. Oral submucous fibrosis causes, symptoms, treatment and. Oral submucous fibrosis a disease with malignant potential.
Oral submucous fibrosis osmf is a chronic, progressive disease that alters the fibroelasticity of the oral submucosa, prevalent in india and southeast asia but rare elsewhere, and characterized by burning and pain in the oral cavity, loss of gustatory sensation, the presence of blanched fibrous bands and stiffening of the oral mucosa and oropharynx leading to trismus and a progressive. It is suggested that submucous fibrosis should be regarded as a condition that causes predisposition to the development of oral cancer. Oral submucous fibrosis is an established precancerous condition with increased prevalence in the indian subcontinent. Ramanathan summary submucous fibrosis smf an important precancerous condition occurs almost exclusively in indians but cases have been reportedfrom several countries throughout the world. American multidisciplinary international research journal 2014. Efficacy of hyaluronidase combined with corticosteroids in treatment of oral submucous fibrosis. Oral dysplasias and squamous cell carcinomas are complications of oral submucous fibrosis.
Joshi 2 subsequently termed the condition oral submucous fibrosis osf in 1953. Oral submucous fibrosis osf is a premalignant condition caused by betel chewing. R crri,saveetha dental college and hospitals, chennai abstract. If the disease is detected at a very early stage, cessation of the habit is sufficient. The patient must be actively discour aged from chewing areca nut preparations. Oral submucous fibrosis osmf is a chronic, progressive, scarring, high risk precancerous condition of oral mucosa seen primarily in indian subcontinent, southeast asia, taiwan, southeast china and papua new guinea.
Oral submucous fibrosis osmf is a debilitating condition of oral cavity which has significant potential for malignant transformation. A pilot study on ayurvedic management of oral submucous. Oral submucous fibrosisa case report medcraveonline. Here we are presenting two cases of oral submucous fibrosis showing malignant potential and development of oral squamous cell carcinoma. Tongue flap in oral submucous fibrosis springerlink. A novel clinical protocol for therapeutic intervention in oral. Oral submucous fibrosis medical specialties clinical. Effectiveness of pentoxifylline in the treatment of oral submucous. Various surgical treatment options adopted for remedying this condition include simple excision of fibrous bands and creating lingual pedicle and nasolabial flaps. The treatment of patients with oral submucous fibrosis depends on the degree of clinical involvement. The mouth may feel dry with ulcers on examination, even at an early stage, the oral mucosa looks white in a marblelike pattern, either diffusely throughout the mouth or in localised. Oral sub mucous fibrosis, areca nut, malignant transformation. Oral submucous fibrosis is a chronic, precancerous, and often debilitating condition characterized by slowly progressive fibrosis of the oral cavity and oropharynx. Oral submucous fibrosis osmf, a chronic debilitating condition of the mouth, has been treated both surgically and nonsurgically, but nonsurgical methods yield inconsistent results.
Oral submucous fibrosis osmf is a chronic disease of oral mucosa characterized by inflammation and progressive fibrosis followed by stiffening of an otherwise yielding mucosa resulting in difficulty in opening the. Relationship to risk factors associated with oral cancer. It is noted mainly in the indian subcontinent, southsoutheast asia, taiwan, and southern china. Oral submucous fibrosis osf is a chronic disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. No known treatment for osf is effective, although some conservative and surgical interventions may result. The findings of the present study can be summarised as follows. Oral submucous fibrosis osf is a premalignant condition mainly associated with the practice of chewing betel quid containing areca nut, a habit common among south asian people. The available epidemiological data showed a clearcut geographical and ethnic predisposition, which suggested that certain customshabits prevalent among the population groups in southeast asia might be possible etiological factors. The symptoms and signs depend on the progression of the lesions and number of affected sites. Oral submucous fibrosis is chronic, insidious disease affecting the oral cavity and sometimes the pharynx and rarely the tongue.
Oral submucous fibrosis, classification systems, staging and grading. Comparison of mouth opening with different nonsurgical treatment modalities in oral submucous fibrosis karthik p. Oral submucous fibrosis, a clinically benign but potentially. It is very common in southeast asia but has started to spread to europe and north america. The causes ofsmf are unknown and there is no known treatment for it. It can be used as a replacement for regular cooking oil. Oral submucous fibrosis in a twelveyearold girl aapd. Drug treatment for oral submucous fibrosis abstracted from jiang x, hu j. Oral submucous fibrosis an overview sciencedirect topics. Oral submucous fibrosis is a chronic, complex, premalignant 1% transformation risk condition of the oral cavity, characterized by juxtaepithelial inflammatory reaction and progressive fibrosis of the submucosal tissues the lamina propria and deeper connective tissues. In all 21 cases have been treated with followup of maximum 3 years and. Current protocols in the management of oral submucous fibrosis.
Oral submucous fibrosis is a longlasting disease that affects the mouth. Submitted by sayed nabi ahamed oral submucous fibrosis. Patients with osmf need treatment for trismus correction, reconstructive surgery for any simultaneous oral malignancy. Oral submucous fibrosis osmf is an insidious, chronic, resistant disease characterised by inflammation and progressive fibrosis of the submucosal tissues 1. The predominant species is candida albicans, which has the potential to infect any tissue within the body 6.
Dr j hu, department of oral and maxillofacial surgery, west china college of stomatology, sichuan university, chengdu 610041. Oral submucous fibrosis an alternative hypothesis as to. The initial symptom includes the burning sensation of the oral mucosa which is intensified. A perspective study of role of lateral tongue flap operation in cases with trismus due to oral submucous fibrosis has been carried out. In patients with oral submucous fibrosis, the risk of developing oral carcinoma is 7. Cox s, zoellner h, physiotherapeutic treatment improves oral opening in oral submucous fibrosis, j oral patho med, 38, 2009, 220226. Candida in oral submucous fibrosis discussion healthy individuals carry 347% of candida species as a component of normal oral flora 11. Medical treatment is symptomatic and predominantly aimed at improving mouth movements. These are injected into the fibrotic bands weekly for 68 weeks with regular monitoring of mouth opening. Oral submucous fibrosis and the role of curcumin in its treatment. Areca nuts have also been shown to have a high copper content, and chewing areca nuts for 530 minutes significantly increases soluble copper levels in oral fluids. A total of 96 patients with oral submucous fibrosis have received four regimens of treatmentlocal dexamethasone, local hyaluronidase, local combination of dexamethasone and hyaluronidase, and local placental extract. Surgical fibrolysis and skin grafts in the management of. The disease is regarded as a precancerous and potentially malignant.
Surgical intervention in osmf seemed to follow a predictable treatment plan. Classification of oral submucous fibrosis, fibrous bands, gutkha, osmf, potentially malignant disorder. O ral submucous fibrosis is a chronic, insidious disease affecting the oral cavity and sometimes pharynx. Comparative study of candida in oral submucous fibrosis. Oral submucous fibrosis a study although many studies proved that main causative agent is areca nut. It is characterized by inflammation, increased deposition of submucosal collagen and formation of fibrotic bands in the oral and paraoral tissues, which increasingly limit. The surgical management of this condition involves excision of the fibrotic bands and interpositional grafts to retain the increased oral opening. Ifngamma, through its effect of altering collagen synthesis, appears to be a key factor to the treatment of patients with oral submucous fibrosis. This study includes pre and postoperative evaluation of 21 cases. Efficacy of salvianolic acid b combined with triamcinolone acetonide in the treatment of oral submucous fibrosis.
Oral submucous fibrosis osmf, oral fibrosis introduction oral submucous fibrosis is a chronic disease of insidious onset featuring the deposition of fibrous tissue in the submucous layer of the palate, fauces, cheek, lips, pharynx and esophagus. Oral submucous fibrosis and the role of curcumin in its. This plays a role in the treatment of patients with oral submucous fibrosis because of its immunoregulatory effect. In 1952, schwart 1 first coined the term atrophica idiopathica mucosa oris to describe an oral fibrotic disease from kenya. Patients are advised to do mouthopening exercises, for example, by placing ice.
The underlying muscles of mastication may be affected resulting in trismus and disability. Le pv, gornitsky m, oral stent as treatment adjunct for oral submucous fibrosis, oral surg oral med oral pathol oral radiol endod, 81, 1996, 148150. Oral submucous fibrosis and its various treatment modalities inclusive of both nonsurgical and surgical management. Oral submucous fibrosis osmf is a chronic debilitating disease and a wellrecognized potentially premalignant condition of the oral cavity. Oral submucous fibrosis is a chronic insidious disease which was previously designated as a premalignant condition but presently categorized under potentially malignant disorders who 2005. Oral submucous fibrosis is a chronic disorder characterized by progressive fibrosis of the lining mucosa of the upper digestive tract involving the oral cavity, oropharynx, and frequently the. Excision of fibrotic bands was the primary procedure. It makes the mouth rigid and towards the end the patient would find it unable to open the mouth. Dr saikat saha mds, omfs, siliguri slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Use of diode lasers in treatment of oral submucous. The first symptom of oral submucous fibrosis is a burning sensation in the mouth especially when eating spicy food, sometimes also with small blister formation. For oral submucous fibrosis we have nonsurgical and surgical treatment options depending on severity of diesase for natural treatment we suggest flax seed oil used to massage that area. Oral submucous fibrosis osmf is a potentially malignant disorder largely seen in the southasian countries where areca nut is found to be the main. Efficacy of lycopene in the management of oral submucous fibrosis.
Oral submucous fibrosis osmf is a chronic, progressive, debilitating, scarring and crippling disorder of the oral cavity. Analysis of buccal fat pad used for treatment of oral submucous fibrosis in literature of the reports, seven studies also used adjunctive myotomy and coronoidotomy during the treatment. O r nasolabial island flap in the management of oral. Oral submucous fibrosis ia a chronic disease in the oral cavity and includes the inflamation and progressive fibrosis of the submucosal tissue. Oral submucous fibrosis osmf is a potentially malignant disorder of the oral cavity. The surgical methods essentially comprise of bilateral sectioning of fibrous bands with or without coronoidectomy followed by covering of the surgical defect with a graft or a wound dressing material such as collagen sheet. It is associated with arecabetel nut chewing, areca nut being the main component of betel quid. I am suffering from osmf, so i would like to take homeopathy treatment first. Oral yeasts are known to be associated with systemic and localized oral disease.
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